Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215053 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BKMT2APMM2 | |
| SCHEMBL25202981 | 0.84 | HTR2A (0.48) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4166591 | 0.82 | HTR2A (0.47) | HTR2AHTR2CHTR2BKMT2AKEAP1 | |
| SCHEMBL29614959 | 0.82 | KEAP1 (0.53) | HTR2AHTR2CHTR2BKMT2ANOTUM | |
| SCHEMBL15976503 | 0.82 | HTR2A (0.47) | HTR2AHTR2CHTR2BKEAP1NFE2L2 | |
| SCHEMBL44782 | 0.82 | KEAP1 (0.53) | HTR2AHTR2CHTR2BKMT2ANOTUM | |
| SCHEMBL17632850 | 0.81 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL19031388 | 0.81 | HTR2A (0.57) | HTR2AHTR2CHTR2BKMT2AKEAP1 | |
| SCHEMBL25199877 | 0.81 | HTR2A (0.51) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 | |
| SCHEMBL31095350 | 0.81 | HTR2A (0.51) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |