Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25196835 | 1.00 | ALDH1A1 (0.51) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL25197267 | 0.88 | ALDH1A1 (0.46) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL25214611 | 0.85 | ALDH1A1 (0.46) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL20589712 | 0.85 | HTR2A (0.48) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL25203794 | 0.85 | HTR2A (0.46) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL31095351 | 0.85 | HTR2A (0.48) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL25198704 | 0.84 | PKM (0.46) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL20589833 | 0.84 | HTR2A (0.46) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL25191480 | 0.81 | HTR2A (0.54) | ALDH1A1PKMHTR2AHTR2CHTR2B | |
| SCHEMBL25194715 | 0.81 | HTR2A (0.48) | ALDH1A1PKMHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |