Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | ABL2 | P42684 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211896 | 1.00 | ABL1 (0.44) | ABL1EGFRCDK1SRCABL2 | |
| SCHEMBL15976500 | 0.84 | AOC2 (0.33) | ABL1EGFRCDK1SRCABL2 | |
| SCHEMBL25192825 | 0.80 | VHL (0.48) | ABL1EGFRCDK1SRCABL2 | |
| SCHEMBL8243459 | 0.78 | KDM4E (0.48) | CFTR | |
| SCHEMBL9454807 | 0.76 | CFTR (0.49) | ABL1EGFRCDK1SRCABL2 | |
| SCHEMBL31095502 | 0.76 | HTR2A (0.47) | ABL1EGFRCDK1SRCABL2 | |
| SCHEMBL25200436 | 0.76 | HTR2A (0.47) | ABL1EGFRCDK1SRCABL2 | |
| SCHEMBL25202979 | 0.76 | PI4KA (0.47) | — | |
| SCHEMBL31095252 | 0.76 | PI4KA (0.47) | — | |
| SCHEMBL25512847 | 0.76 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |