Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25194557 | 1.00 | HTR2A (0.44) | HTR2AHTR2CHTR2BMAPTRIPK2 | |
| SCHEMBL25194715 | 0.86 | HTR2A (0.48) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL25191480 | 0.83 | HTR2A (0.54) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL25200431 | 0.82 | KEAP1 (0.52) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL31095257 | 0.82 | KEAP1 (0.52) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL20589447 | 0.81 | HTR2A (0.44) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL25195386 | 0.81 | HTR2A (0.44) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL31095519 | 0.81 | HTR2A (0.44) | HTR2AHTR2CHTR2BMAPTALDH1A1 | |
| SCHEMBL22237339 | 0.77 | CYP2E1 (0.55) | RIPK2CHRNB2CHRNA4MAOAMAOB | |
| SCHEMBL25196835 | 0.77 | ALDH1A1 (0.51) | HTR2AHTR2CHTR2BMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |