Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211906 | 0.75 | HTR2A (0.42) | HTR2AHTR2CHTR2BL3MBTL1ALDH1A1 | |
| SCHEMBL25191885 | 0.73 | HTR2A (0.43) | HTR2AHTR2CHTR2BL3MBTL1ALDH1A1 | |
| SCHEMBL2159987 | 0.71 | HTR2A (0.44) | HTR2AHTR2CHTR2BL3MBTL1TAAR1 | |
| SCHEMBL31095390 | 0.71 | ALDH1A1 (0.49) | ALDH1A1PKMKDM4E | |
| SCHEMBL44903 | 0.70 | — | — | |
| SCHEMBL27932470 | 0.69 | — | — | |
| SCHEMBL5666548 | 0.69 | HTR2A (0.53) | HTR2AHTR2CHTR2BL3MBTL1ALDH1A1 | |
| SCHEMBL19031388 | 0.68 | HTR2A (0.57) | HTR2AHTR2CHTR2BL3MBTL1ALDH1A1 | |
| SCHEMBL25196968 | 0.68 | HTR2A (0.47) | HTR2AHTR2CHTR2BL3MBTL1ALDH1A1 | |
| SCHEMBL7240483 | 0.68 | LMNA (0.42) | HTR2AHTR2CHTR2BALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |