Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067224 | 0.88 | C5AR1 (0.43) | GRM5C5AR1MAPTEEDKMT2A | |
| SCHEMBL23413092 | 0.85 | P2RX7 (0.42) | GRM5MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL1831804 | 0.77 | C5AR1 (0.60) | C5AR1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31095294 | 0.77 | C5AR1 (0.60) | C5AR1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31230012 | 0.73 | KDM4E (0.59) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL22435548 | 0.73 | KDM4E (0.59) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL31067183 | 0.72 | MAOB (0.37) | C5AR1SMN1; SMN2 | |
| SCHEMBL1831603 | 0.72 | C5AR1 (0.61) | C5AR1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23074954 | 0.71 | C5AR1 (0.54) | C5AR1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL1830949 | 0.71 | ALDH1A1 (0.39) | MAPTKMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |