Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28159356 | 0.85 | CA2 (0.54) | HSD17B10CA2APPHDAC1CYP2A6 | |
| SCHEMBL31095701 | 0.82 | HDAC1 (0.35) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11886144 | 0.77 | CA2 (0.42) | HSD17B10CA2APPHDAC1CYP2A6 | |
| SCHEMBL3597089 | 0.77 | HSD17B10 (0.50) | HSD17B10CA2APPHDAC1CYP2A6 | |
| SCHEMBL25225674 | 0.77 | HSD17B10 (0.42) | HSD17B10CA2APPHDAC1CYP2A6 | |
| SCHEMBL27256109 | 0.74 | HDAC3 (0.53) | APPHDAC1CYP2A6HDAC3HDAC4 | |
| SCHEMBL31207829 | 0.73 | TBXAS1 (0.57) | HSD17B10HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL191611 | 0.73 | TBXAS1 (0.57) | HSD17B10HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL18878582 | 0.73 | CYP2A6 (0.41) | APPCYP2A6 | |
| SCHEMBL15391504 | 0.73 | ESR1 (0.39) | APPHDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680247-A1 | DPP1 INHIBITORS WITH POLYCYCLIC LINKERS AND USES THEREOF | Insmed Incorporated (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192416-A1 | DPP1 INHIBITORS WITH POLYCYCLIC LINKERS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-09-19 | — | — | WO | disclosed |