Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097191 | 0.90 | PREP (0.49) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097167 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097194 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL27190405 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL29239602 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL27190317 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097140 | 0.82 | PREP (0.48) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL29580866 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AL3MBTL1CYP2C19 | |
| SCHEMBL9132544 | 0.80 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9APREPTSHR | |
| SCHEMBL31097159 | 0.80 | PREP (0.48) | SMN1; SMN2NPC1RAB9APREPACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294498-A1 | FACTOR XIIA INHIBITORS | LUNAC THERAPEUTICS LTD (GB) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294498-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F7 | SMN1; SMN2 4362/4885NPC1 3933/4885RAB9A 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.