Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TCF7 | P36402 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904751 | 0.88 | CTNNB1 (0.54) | CTNNB1TCF7MPOKDM1ACCNC | |
| SCHEMBL29728749 | 0.88 | CTNNB1 (0.54) | CTNNB1TCF7MPOKDM1ACCNC | |
| SCHEMBL29585470 | 0.76 | MPO (0.49) | CTNNB1TCF7MPOKDM1ACCNC | |
| SCHEMBL904805 | 0.76 | MPO (0.49) | CTNNB1TCF7MPOKDM1ACCNC | |
| SCHEMBL904745 | 0.75 | HTR2A (0.43) | CTNNB1TCF7HTR2ACACNA1H | |
| SCHEMBL13476250 | 0.75 | CTNNB1 (0.58) | CTNNB1TCF7MPOCCNCHTR2A | |
| SCHEMBL31638220 | 0.75 | CTNNB1 (0.58) | CTNNB1TCF7MPOCCNCHTR2A | |
| SCHEMBL30855622 | 0.75 | EGFR (0.38) | CTNNB1TCF7HTR2ACDC7TRPM5 | |
| SCHEMBL6340738 | 0.73 | CTNNB1 (0.56) | CTNNB1TCF7MPOKDM1ACCNC | |
| SCHEMBL8179108 | 0.73 | CTNNB1 (0.55) | CTNNB1TCF7MPOCCNCHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294498-A1 | FACTOR XIIA INHIBITORS | LUNAC THERAPEUTICS LTD (GB) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294498-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F7 | CTNNB1 4363/4885TCF7 286/4885MPO 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.