Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097402 | 0.85 | JAK3 (0.37) | CHEK1 | |
| SCHEMBL4342337 | 0.70 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL3070658 | 0.64 | CHEK1 (0.46) | CHEK1 | |
| SCHEMBL31052385 | 0.63 | LCK (0.35) | — | |
| SCHEMBL31052405 | 0.63 | LCK (0.35) | — | |
| SCHEMBL4353898 | 0.63 | GSK3B (0.41) | CHEK1 | |
| SCHEMBL14543510 | 0.62 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL4341481 | 0.62 | PIK3CD (0.41) | CHEK1 | |
| SCHEMBL14373172 | 0.62 | LRRK2 (0.34) | — | |
| SCHEMBL31039919 | 0.62 | JAK3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580252-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 百极弘烨(南通)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |