Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 16/20 | 0.41 |
| ▸ | LCK | P06239 | 15/20 | 0.41 |
| ▸ | BTK | Q06187 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 9/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052405 | 0.84 | LCK (0.35) | JAK3LCKBTKEGFR | |
| SCHEMBL31052385 | 0.84 | LCK (0.35) | JAK3LCKBTKEGFR | |
| SCHEMBL28647032 | 0.81 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL29931205 | 0.81 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL30165882 | 0.79 | LCK (0.40) | JAK3LCKBTKHRH3EGFR | |
| SCHEMBL30161265 | 0.79 | JAK3 (0.46) | JAK3LCKBTKHRH3EGFR | |
| SCHEMBL30160837 | 0.79 | JAK3 (0.51) | JAK3LCKBTKEGFR | |
| SCHEMBL30160933 | 0.78 | JAK3 (0.42) | JAK3LCKBTKHRH3EGFR | |
| SCHEMBL30160867 | 0.78 | JAK3 (0.42) | JAK3LCKBTKHRH3EGFR | |
| SCHEMBL30165812 | 0.78 | FAAH (0.47) | JAK3LCKBTKHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955473-A | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |