Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 15/20 | 0.37 |
| ▸ | LCK | P06239 | 14/20 | 0.37 |
| ▸ | BTK | Q06187 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 7/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097391 | 0.85 | CHEK1 (0.32) | CHEK1 | |
| SCHEMBL24833595 | 0.76 | JAK3 (0.43) | JAK3LCKBTKEGFR | |
| SCHEMBL31097397 | 0.75 | RET (0.44) | JAK3LCKBTKEGFRCHEK1 | |
| SCHEMBL24833599 | 0.75 | JAK3 (0.42) | JAK3LCKBTKEGFR | |
| SCHEMBL30160648 | 0.75 | JAK3 (0.42) | JAK3LCKBTKEGFR | |
| SCHEMBL23460213 | 0.73 | JAK3 (0.40) | JAK3LCKBTKEGFR | |
| SCHEMBL24833597 | 0.72 | JAK3 (0.40) | JAK3LCKBTKJAK2 | |
| SCHEMBL24834042 | 0.71 | KDM4E (0.39) | JAK3LCKBTKEGFR | |
| SCHEMBL4342337 | 0.70 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL24834051 | 0.70 | KDM4E (0.38) | JAK3LCKBTKEGFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580252-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 百极弘烨(南通)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |