Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 10/20 | 0.40 |
| ▸ | LCK | P06239 | 7/20 | 0.40 |
| ▸ | BTK | Q06187 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097395 | 0.90 | CHEK1 (0.51) | RETJAK3LCKBTKCHEK1 | |
| SCHEMBL31097402 | 0.75 | JAK3 (0.37) | JAK3LCKBTKCHEK1EGFR | |
| SCHEMBL21946793 | 0.74 | JAK3 (0.71) | JAK3LCKBTKEGFR | |
| SCHEMBL29931224 | 0.74 | JAK3 (0.71) | JAK3LCKBTKEGFR | |
| SCHEMBL21855409 | 0.69 | JAK3 (0.65) | JAK3LCKBTKEGFR | |
| SCHEMBL29872120 | 0.69 | JAK3 (0.78) | JAK3LCKBTKEGFR | |
| SCHEMBL21855411 | 0.69 | JAK3 (0.78) | JAK3LCKBTKEGFR | |
| SCHEMBL4350029 | 0.68 | PIK3CD (0.49) | CHEK1GPR119 | |
| SCHEMBL25603497 | 0.68 | JAK3 (0.62) | JAK3LCKBTKEGFR | |
| SCHEMBL25606266 | 0.67 | JAK3 (0.61) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580252-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 百极弘烨(南通)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |