Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098233 | 0.97 | DRD4 (0.45) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098242 | 0.90 | HTR2C (0.47) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098243 | 0.86 | DRD2 (0.60) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098232 | 0.78 | HRH4 (0.56) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL7408774 | 0.77 | HRH4 (0.69) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098236 | 0.77 | DRD2 (0.69) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL3837735 | 0.75 | HRH4 (0.61) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098245 | 0.74 | DRD3 (0.51) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098208 | 0.74 | DRD2 (0.64) | DRD4DRD3DRD2CHRM1HRH4 | |
| SCHEMBL31098225 | 0.74 | HRH4 (0.64) | DRD4DRD3DRD2CHRM1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4428132-A1 | SLACK-ACTIVATING COMPOUNDS AND THEIR MEDICAL USE | Johann-Wolfgang-Goethe-Universität Frankfurt am Main (DE) | 2024-09-11 | — | — | EP | disclosed |