Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 8/20 | 0.41 |
| ▸ | HRH1 | P35367 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098219 | 0.90 | DRD4 (0.48) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL31098232 | 0.88 | HRH4 (0.56) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL31098233 | 0.87 | DRD4 (0.45) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL31098241 | 0.80 | HTR2C (0.52) | HTR2CHRH4HTR2AHRH1 | |
| SCHEMBL31098211 | 0.78 | HTR2C (0.53) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL31098240 | 0.78 | HRH4 (0.69) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL31098243 | 0.76 | DRD2 (0.60) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL3837735 | 0.70 | HRH4 (0.61) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL4173790 | 0.69 | HRH4 (0.54) | HTR2CHRH4HTR2AHRH1DRD4 | |
| SCHEMBL3840090 | 0.69 | HRH4 (0.52) | HTR2CHRH4HTR2AHRH1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4428132-A1 | SLACK-ACTIVATING COMPOUNDS AND THEIR MEDICAL USE | Johann-Wolfgang-Goethe-Universität Frankfurt am Main (DE) | 2024-09-11 | — | — | EP | disclosed |