Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644596 | 1.00 | HRH4 (0.39) | HRH4KCNH2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15435135 | 0.82 | HRH4 (0.34) | HRH4KCNH2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6856814 | 0.82 | ALDH1A1 (0.47) | KCNH2NPSR1ADORA2APGK1PGK2 | |
| SCHEMBL6984472 | 0.82 | ALDH1A1 (0.47) | KCNH2NPSR1ADORA2APGK1PGK2 | |
| SCHEMBL29100661 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2LMNAMRGPRX4 | |
| SCHEMBL23355545 | 0.78 | TOP2A (0.42) | KCNH2NPSR1ADORA2ASMN1; SMN2LMNA | |
| SCHEMBL29289942 | 0.78 | TERT (0.39) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL28519573 | 0.78 | BACE1 (0.37) | HRH4KCNH2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15856232 | 0.77 | KCNH2 (0.44) | HRH4KCNH2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28520098 | 0.77 | ADORA2A (0.41) | NPSR1ADORA2ACYP1A2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563245-B | Substituted pyrrolidines and their use in medicine | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |