Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25840478 | 0.84 | HDAC3 (0.77) | HPGDLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL10436247 | 0.81 | HDAC3 (0.74) | LMNAHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL25591005 | 0.81 | HPGD (1.00) | HPGDLMNATAAR1POLB | |
| SCHEMBL28119473 | 0.81 | HPGD (0.71) | HPGDLMNATAAR1PLAAT3PLAAT5 | |
| SCHEMBL14893159 | 0.80 | HPGD (0.60) | HPGDLMNACA1CA2CA12 | |
| SCHEMBL658360 | 0.79 | LMNA (0.54) | HPGDLMNATAAR1 | |
| SCHEMBL7011664 | 0.79 | HPGD (0.64) | HPGDLMNAPOLBEPHX2 | |
| SCHEMBL5504740 | 0.79 | KDM4E (0.54) | HPGDCA1CA2CA12CA9 | |
| SCHEMBL8802829 | 0.78 | CA12 (0.75) | HPGDLMNACA1CA2CA12 | |
| SCHEMBL3316967 | 0.78 | HPGD (0.68) | HPGDLMNACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240261307-A1 | INHIBITORS OF SARS-COV-2 VIRAL REPLICATION AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2024-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240261307-A1 | INHIBITORS OF SARS-COV-2 VIRAL REPLICATION AND USES THEREOF | ACE2, ACE, TMPRSS2 | HPGD 1314/4885LMNA 3413/4885HDAC3 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.