Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.35 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.33 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31104008 | 0.87 | PSMD10 (0.36) | PSMD10SLC12A2SLC12A5CASP3CASP7 | |
| SCHEMBL31104491 | 0.80 | RXRA (0.34) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL31104342 | 0.78 | ALDH1A1 (0.38) | PDE1APDE1BPDE1CCYP4F2CYP4A11 | |
| SCHEMBL31103876 | 0.78 | ALDH1A1 (0.38) | PDE1APDE1BPDE1CCYP4F2CYP4A11 | |
| SCHEMBL31104287 | 0.76 | ALDH1A1 (0.36) | KDM4EPDE1APDE1BPDE1CCYP4F2 | |
| SCHEMBL31104017 | 0.74 | ALDH1A1 (0.40) | PDE1APDE1BPDE1CCYP4F2CYP4A11 | |
| SCHEMBL22070538 | 0.70 | CYP4F2 (0.56) | CYP4F2CYP4A11 | |
| SCHEMBL11016658 | 0.67 | MEN1 (0.47) | PSMD10SLC12A2SLC12A5CASP3CASP7 | |
| SCHEMBL15633060 | 0.67 | SLC12A2 (0.37) | SLC12A2SLC12A5KDM4ECYP4F2CYP4A11 | |
| SCHEMBL31103919 | 0.67 | ALDH1A1 (0.40) | PDE1APDE1BPDE1CCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059161-A1 | COMPOUNDS AND METHODS FOR MODULATING STAT3 | VIVIDION THERAPEUTICS, INC. | 2025-02-20 | — | — | US | disclosed |
| WO-2024182693-A1 | 2-AZASPIRO[3.3]HEPTANE DERIVATIVES AS STAT3 INHIBITORS FOR THE TREATMENT OF CANCER | VIVIDION THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059161-A1 | COMPOUNDS AND METHODS FOR MODULATING STAT3 | STAT3, JAK2, STAT1 | PSMD10 3643/4885SLC12A2 3728/4885SLC12A5 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.