Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19174930 | 0.87 | PDK1 (0.44) | CYP3A4TSHRALDH1A1LMNATDP1 | |
| SCHEMBL1491795 | 0.81 | ALDH1A1 (0.54) | CYP3A4TSHRALDH1A1LMNATDP1 | |
| SCHEMBL15174114 | 0.78 | TSHR (0.59) | CYP3A4TSHRALDH1A1LMNAMAPT | |
| SCHEMBL31104710 | 0.78 | MAPT (0.39) | CYP3A4TSHRALDH1A1LMNATDP1 | |
| SCHEMBL30184600 | 0.77 | TSHR (0.41) | CYP3A4TSHRALDH1A1LMNATDP1 | |
| SCHEMBL29212369 | 0.77 | TSHR (0.41) | CYP3A4TSHRALDH1A1LMNATDP1 | |
| SCHEMBL29446158 | 0.76 | TDP1 (0.55) | CYP3A4TSHRALDH1A1TDP1MAPT | |
| SCHEMBL2229339 | 0.76 | TDP1 (0.55) | CYP3A4TSHRALDH1A1TDP1MAPT | |
| SCHEMBL19175567 | 0.75 | NPC1 (0.47) | ALDH1A1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL25033449 | 0.75 | ALDH1A1 (0.32) | CYP3A4TSHRALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676602-A1 | COMPOUNDS TARGETING MUTATIONS IN P53 AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024187153-A1 | COMPOUNDS TARGETING MUTATIONS IN P53 AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-09-12 | — | — | WO | disclosed |