Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 8/20 | 0.45 |
| ▸ | BTK | Q06187 | 9/20 | 0.44 |
| ▸ | LCK | P06239 | 7/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105889 | 0.91 | HCK (0.44) | HCKBTKLCKABL1 | |
| SCHEMBL31105983 | 0.85 | HCK (0.36) | HCKBTKLCKF10ABL1 | |
| SCHEMBL31105907 | 0.84 | BTK (0.48) | HCKBTKLCK | |
| SCHEMBL31106147 | 0.82 | HCK (0.39) | HCKBTKLCKABL1 | |
| SCHEMBL31105927 | 0.82 | HCK (0.44) | HCKBTKLCKABL1 | |
| SCHEMBL31105878 | 0.82 | HCK (0.39) | HCKBTKLCKABL1DDR1 | |
| SCHEMBL31106032 | 0.81 | HCK (0.38) | HCKBTKLCKABL1 | |
| SCHEMBL31105900 | 0.81 | BTK (0.46) | HCKBTKLCKABL1 | |
| SCHEMBL31105903 | 0.80 | LCK (0.38) | HCKBTKLCKABL1 | |
| SCHEMBL31105912 | 0.79 | MAPK14 (0.50) | HCKBTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |