Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | SIK1 | P57059 | 3/20 | 0.35 |
| ▸ | SIK2 | Q9H0K1 | 3/20 | 0.35 |
| ▸ | SIK3 | Q9Y2K2 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 10/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106032 | 0.93 | HCK (0.38) | HCKBTKRXRARXRBRXRG | |
| SCHEMBL31105927 | 0.91 | HCK (0.44) | HCKBTKRXRARXRBRXRG | |
| SCHEMBL31105889 | 0.91 | HCK (0.44) | HCKBTKRXRARXRBRXRG | |
| SCHEMBL31105878 | 0.91 | HCK (0.39) | HCKBTKABL1SIK1SIK2 | |
| SCHEMBL31105863 | 0.82 | HCK (0.45) | HCKBTKABL1LCK | |
| SCHEMBL31105897 | 0.82 | RXRA (0.40) | HCKRXRARXRBRXRGLCK | |
| SCHEMBL31106079 | 0.80 | LCK (0.38) | HCKBTKRXRARXRBRXRG | |
| SCHEMBL31105903 | 0.79 | LCK (0.38) | HCKBTKRXRARXRBRXRG | |
| SCHEMBL31106092 | 0.78 | KRAS (0.35) | HCKBTKABL1SIK1SIK2 | |
| SCHEMBL31105893 | 0.74 | LCK (0.41) | HCKRXRARXRBRXRGLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |