Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227895 | 0.82 | RXRA (0.47) | KMT2ARXRARXRBRXRGPOLB | |
| SCHEMBL31430725 | 0.82 | RXRA (0.42) | LCKSMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL31430803 | 0.82 | RXRA (0.40) | RXRARXRBRXRGPOLBCYP4F2 | |
| SCHEMBL31105893 | 0.81 | LCK (0.41) | LCKRXRARXRBRXRGCYP4F2 | |
| SCHEMBL31737727 | 0.81 | RXRA (0.39) | LCKRXRARXRBRXRGCYP4F2 | |
| SCHEMBL31738052 | 0.78 | RXRA (0.37) | LCKRXRARXRBRXRGPOLB | |
| SCHEMBL31105912 | 0.77 | MAPK14 (0.50) | LCKRXRARXRBRXRGCYP4F2 | |
| SCHEMBL25787278 | 0.77 | CYP4F2 (0.43) | KMT2ARXRARXRBRXRGMEN1 | |
| SCHEMBL30860912 | 0.76 | RXRA (0.41) | LCKRXRARXRBRXRGCYP4F2 | |
| SCHEMBL31705188 | 0.76 | LCK (0.52) | LCKSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |