Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689024 | 0.83 | HTR1A (0.41) | HTR1ADRD2DRD4ASIC3MCHR1 | |
| SCHEMBL20689022 | 0.83 | HTR1A (0.41) | HTR1ADRD2DRD4ASIC3MCHR1 | |
| SCHEMBL20688105 | 0.83 | HTR1A (0.41) | HTR1ADRD2DRD4ASIC3MCHR1 | |
| SCHEMBL3925163 | 0.81 | ASIC3 (0.43) | HTR1ADRD2DRD4ASIC3NOS3 | |
| SCHEMBL29900984 | 0.81 | ASIC3 (0.43) | HTR1ADRD2DRD4ASIC3NOS3 | |
| SCHEMBL10008729 | 0.81 | HTR1A (0.53) | HTR1ADRD2DRD4ASIC3NOS3 | |
| SCHEMBL15091015 | 0.78 | HTR1A (0.41) | HTR1ADRD2DRD4ASIC3NOS3 | |
| SCHEMBL21988030 | 0.76 | HTR1A (0.46) | HTR1ADRD2DRD4ASIC3NOS3 | |
| SCHEMBL31543163 | 0.76 | KDM1A (0.30) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL30279700 | 0.76 | HTR1A (0.46) | HTR1ADRD2DRD4ASIC3NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |