Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4546558 | 1.00 | CTSS (0.52) | CTSSCTSKCTSBBCL2ACE | |
| SCHEMBL10156301 | 0.89 | KLK5 (0.55) | CTSSCTSKCTSBBCL2ACE | |
| SCHEMBL29722671 | 0.88 | ACE (0.60) | CTSSCTSKCTSBBCL2ACE | |
| SCHEMBL28789425 | 0.88 | ACE (0.60) | CTSSCTSKCTSBBCL2ACE | |
| SCHEMBL4546557 | 0.88 | ACE (0.60) | CTSSCTSKCTSBBCL2ACE | |
| SCHEMBL14999574 | 0.86 | POLB (0.47) | ACETACR1POLBMAPT | |
| SCHEMBL1827307 | 0.86 | P2RX7 (0.53) | CTSSCTSKCTSBBCL2ACE | |
| SCHEMBL20905929 | 0.86 | CTSS (0.56) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL14576685 | 0.86 | CTSS (0.56) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL30051055 | 0.86 | CTSS (0.56) | CTSSCTSKCTSBACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684605-A | Preparation of ritgasan Process for the preparation of intermediates | 山东新时代药业有限公司 | 2024-09-24 | — | — | CN | disclosed |