SCHEMBL31107112

SCHEMBL31107112

CCOC(=O)c1ccc(Oc2ccc(Cl)cc2)cc1C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.48
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
MAPK1 P28482 1/20 0.45
CYP1A2 P05177 2/20 0.45
POLB P06746 1/20 0.45
TSHR P16473 2/20 0.44
ABCB11 O95342 1/20 0.44
CYP3A4 P08684 1/20 0.44
HTR2A P28223 1/20 0.44
PMP22 Q01453 1/20 0.44
PPARA Q07869 1/20 0.44
MAPT P10636 1/20 0.41
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28665319 0.85 AR (0.51) ARALDH1A1SMN1; SMN2MAPK1HTR2A
SCHEMBL28039336 0.84 AR (0.50) ARCYP3A4HTR2APPARAGAA
SCHEMBL11230963 0.84 MAPK1 (0.51) ALDH1A1LMNASMN1; SMN2GPR55MAPK1
SCHEMBL29741809 0.82 AR (0.54) ARMAPT
SCHEMBL14645660 0.82 AR (0.54) ARMAPT
SCHEMBL29093106 0.82 AR (0.56) ARSMN1; SMN2POLBTSHRPPARA
SCHEMBL366843 0.81 SCN9A (0.49) LMNAABCB11PPARAMAPTCYP4F2
SCHEMBL28661823 0.81 AR (0.55) ARCYP1A2CYP3A4HTR2APPARA
SCHEMBL28036772 0.79 AR (0.56) ARALDH1A1CYP1A2HTR2AKDM4E
SCHEMBL14645459 0.79 AR (0.50) ARCYP3A4HTR2APPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677472-B Synthesis method of drug intermediate and application of drug intermediate in synthesis of penconazole 辽宁大学 2024-08-06 CN claimed
CN-115677472-B Synthesis method of drug intermediate and application of drug intermediate in synthesis of penconazole 辽宁大学 2024-08-06 CN disclosed
CN-115677472-B Synthesis method of drug intermediate and application of drug intermediate in synthesis of penconazole 辽宁大学 2024-08-06 CN disclosed