Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | ARAF | P10398 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741809 | 1.00 | AR (0.54) | ARMAOAMAOBESRRATLR8 | |
| SCHEMBL20000656 | 0.90 | ESRRA (0.46) | ARMAOAMAOBESRRATLR8 | |
| SCHEMBL29093106 | 0.88 | AR (0.56) | ARTLR8FLT1FLT4KDR | |
| SCHEMBL28036772 | 0.88 | AR (0.56) | ARMAOAMAOBESRRATLR8 | |
| SCHEMBL28661823 | 0.87 | AR (0.55) | ARTLR8BRAFHDAC1HDAC3 | |
| SCHEMBL18970462 | 0.87 | MGLL (0.44) | ARMAOAMAOBESRRATLR8 | |
| SCHEMBL22407060 | 0.87 | CES2 (0.50) | ARMAOBESRRATLR8KMT2A | |
| SCHEMBL22115444 | 0.86 | AR (0.42) | ARMAOAMAOBESRRATLR8 | |
| SCHEMBL28665319 | 0.86 | AR (0.51) | ARESRRATLR8MAPK10FLT1 | |
| SCHEMBL22407077 | 0.85 | MAOB (0.43) | ARMAOAMAOBESRRATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069588-A | Preparation method and application of 4-nitro-2-trifluoromethyl acetophenone | 合力科技股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| WO-2023216064-A1 | METHOD FOR PREPARING 4-NITRO-2-TRIFLUOROMETHYL ACETOPHENONE AND USE THEREOF | 合力科技股份有限公司 | 2023-11-16 | — | — | WO | claimed |
| CN-116354896-A | Technological method for preparing penconazole by continuous flow micro-channel | 西安近代化学研究所 | 2023-06-30 | — | — | CN | claimed |
| WO-2024083545-A1 | PROCESS FOR THE PREPARATION OF 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL GRIGNARD COMPOUND AND DERIVATIVES THEREOF | BASF Agro B.V. (NL) | 2024-04-25 | — | — | WO | disclosed |
| US-11840507-B2 | Process for the preparation of phenyl ketones | ARXADA AG (CH) | 2023-12-12 | — | — | US | disclosed |
| US-11840507-B2 | Process for the preparation of phenyl ketones | ARXADA AG (CH) | 2023-12-12 | — | — | US | disclosed |
| CN-117069556-A | Preparation method and application of alkylaryl ketone compound | 合力科技股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069614-A | Preparation method and application of 2-substituted aryl acetonitrile compound | 合力科技股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023216064-A1 | METHOD FOR PREPARING 4-NITRO-2-TRIFLUOROMETHYL ACETOPHENONE AND USE THEREOF | 合力科技股份有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023216064-A1 | METHOD FOR PREPARING 4-NITRO-2-TRIFLUOROMETHYL ACETOPHENONE AND USE THEREOF | 合力科技股份有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023216063-A1 | METHOD FOR PREPARING 2-SUBSTITUTED ARYL ACETONITRILE COMPOUND AND USE THEREOF | 合力科技股份有限公司 | 2023-11-16 | — | — | WO | disclosed |
| US-20150344445-A1 | COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND | BASF Agro B.V. (NL) | 2015-12-03 | — | — | US | disclosed |
| EP-2943476-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OXIRANES AND TRIAZOLES | BASF Agro B.V. (NL) | 2015-11-18 | — | — | EP | disclosed |
| EP-2934147-A1 | COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND | BASF Agro B.V. (NL) | 2015-10-28 | — | — | EP | disclosed |
| WO-2015091045-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENOXYPHENYL KETONES | BASF Agro B.V. (NL) | 2015-06-25 | — | — | WO | disclosed |
| WO-2014108286-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OXIRANES AND TRIAZOLES | BASF SE (DE) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014095994-A1 | COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| US-20140155262-A1 | Fungicidal substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds | BASF SE (DE) | 2014-06-05 | — | — | US | disclosed |
| EP-2731935-A1 | FUNGICIDAL SUBSTITUTED 2-[2-HALOGENALKYL-4-(PHENOXY)-PHENYL]-1-[1,2,4]TRIAZOL-1-YL-ETHANOL COMPOUNDS | BASF SE (DE) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013007767-A1 | FUNGICIDAL SUBSTITUTED 2-[2-HALOGENALKYL-4-(PHENOXY)-PHENYL]-1-[1,2,4]TRIAZOL-1-YL-ETHANOL COMPOUNDS | BASF SE (DE) | 2013-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155262-A1 | Fungicidal substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds | CYP2E1, TH, CYP1A1 | AR 3165/4885MAOA 425/4885MAOB 663/4885 |
| US-20150344445-A1 | COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND | CYP1B1, CYP3A5, CYP4B1 | AR 1808/4885MAOA 94/4885MAOB 92/4885 |
| US-11840507-B2 | Process for the preparation of phenyl ketones | PAH, PDK4, PKM | AR 2287/4885MAOA 390/4885MAOB 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.