SCHEMBL28039336

SCHEMBL28039336

CCC(=O)c1ccc(Oc2ccc(Cl)cc2)cc1C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.50
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
CCNC P24863 1/20 0.43
CDK8 P49336 1/20 0.43
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
KCNH2 Q12809 1/20 0.40
BRAF P15056 1/20 0.40
HDAC1 Q13547 1/20 0.40
MAPK10 P53779 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
TLR8 Q9NR97 1/20 0.39
CYP3A4 P08684 1/20 0.39
FLT1 P17948 1/20 0.38
FLT4 P35916 1/20 0.38
KDR P35968 1/20 0.38
PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29879873 0.86 AR (0.50) ARTHRATHRBGAANPSR1
SCHEMBL14645459 0.86 AR (0.50) ARTHRATHRBGAANPSR1
SCHEMBL29741809 0.85 AR (0.54) ARBRAFHDAC1MAPK10TLR8
SCHEMBL14645660 0.85 AR (0.54) ARBRAFHDAC1MAPK10TLR8
SCHEMBL29093106 0.84 AR (0.56) ARTLR8FLT1FLT4KDR
SCHEMBL31107112 0.84 AR (0.48) ARGAANPSR1HTR2ACYP3A4
SCHEMBL26020575 0.84 RAB9A (0.47) THRATHRBGAANPSR1KCNH2
SCHEMBL28661823 0.83 AR (0.55) ARHTR2ASLC6A4KCNH2BRAF
SCHEMBL28665319 0.82 AR (0.51) ARCCNCCDK8HTR2ASLC6A4
SCHEMBL5255602 0.82 MAOB (0.52) CCNCCDK8KCNH2MMP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109503519-A The method for preparing substituted epoxy ethane and triazole type 巴斯夫农业公司 2019-03-22 CN disclosed
CN-104968651-A Process for preparing substituted oxiranes and triazoles BASF SE 2015-10-07 CN disclosed