Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166071 | 1.00 | BRD4 (0.40) | BRD4CREBBPKMT2AMEN1HPGD | |
| SCHEMBL25166094 | 0.87 | BRD4 (0.41) | BRD4CREBBPKMT2ATRPV1CA12 | |
| SCHEMBL31107949 | 0.87 | BRD4 (0.41) | BRD4CREBBPKMT2ATRPV1CA12 | |
| SCHEMBL25165968 | 0.85 | BRD4 (0.40) | BRD4CREBBPKMT2AMEN1TRPV1 | |
| SCHEMBL30329861 | 0.85 | BRD4 (0.40) | BRD4CREBBPKMT2AMEN1TRPV1 | |
| SCHEMBL30674772 | 0.79 | ALDH1A1 (0.59) | KMT2AMEN1TRPV1ALDH1A1MAPT | |
| SCHEMBL29120487 | 0.79 | ALDH1A1 (0.59) | KMT2AMEN1TRPV1ALDH1A1MAPT | |
| SCHEMBL8865861 | 0.76 | TRPV1 (0.59) | BRD4CREBBPKMT2ATRPV1CA12 | |
| SCHEMBL25166072 | 0.75 | ACHE (0.43) | ALDH1A1MALT1 | |
| SCHEMBL28998391 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTPDE3BPDE3APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647610-A | Novel modulators of EHMT1 and EHMT2 and therapeutic uses thereof | 探戈医药股份有限公司 | 2024-09-13 | — | — | CN | disclosed |