Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 3/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631534 | 0.99 | GDA (0.48) | GDAGSK3BXDHPOLA1 | |
| SCHEMBL28542110 | 0.99 | GDA (0.48) | GDAGSK3BXDHPOLA1 | |
| SCHEMBL29022774 | 0.99 | GDA (0.48) | GDAGSK3BXDHPOLA1 | |
| SCHEMBL31083063 | 0.78 | GSK3B (0.45) | GSK3B | |
| SCHEMBL27820217 | 0.78 | GDA (0.47) | GDAXDHPOLA1 | |
| SCHEMBL3877450 | 0.77 | ADK (0.43) | GSK3B | |
| SCHEMBL2873813 | 0.77 | ADK (0.43) | GSK3B | |
| SCHEMBL30697964 | 0.77 | KDM4E (0.46) | GDA | |
| SCHEMBL28343030 | 0.77 | KDM4E (0.46) | GDA | |
| Guanine SCHEMBL4359248 | 0.76 | PNP (0.62) | GDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240358735-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240358735-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | MAG, PMP22, B3GAT3 | GDA 1189/4885GSK3B 574/4885XDH 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.