Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL65307 | 1.00 | PNP (0.62) | PNPMEN1KMT2AALDH1A1MAPT | |
| Guanine SCHEMBL28384883 | 1.00 | PNP (0.62) | PNPMEN1KMT2AALDH1A1MAPT | |
| Guanine SCHEMBL4197782 | 0.88 | PNP (0.53) | PNPMEN1KMT2AALDH1A1MAPT | |
| Thioguanine SCHEMBL2936430 | 0.86 | PNP (0.42) | PNPMEN1KMT2AALDH1A1HPGD | |
| Thioguanine SCHEMBL16028922 | 0.86 | PNP (0.42) | PNPMEN1KMT2AALDH1A1HPGD | |
| Guanine SCHEMBL9861048 | 0.85 | PNP (0.52) | PNP | |
| Hypoxanthine SCHEMBL9538156 | 0.85 | ALDH1A1 (0.53) | PNPMEN1KMT2AALDH1A1MAPT | |
| Isoguanine SCHEMBL11527542 | 0.83 | PNP (0.39) | PNPMEN1KMT2AALDH1A1THRB | |
| Guanine SCHEMBL4198112 | 0.83 | PNP (0.58) | PNPMEN1KMT2AALDH1A1MAPT | |
| Cytidine SCHEMBL3129099 | 0.81 | LMNA (0.67) | PNPALDH1A1MAPTTHRBGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397706-A | Serum-free basal and culture medium for hematopoietic and leukemia cells | CORREA PAULO N (CA) | 1995-03-14 | — | — | US | claimed |
| WO-1993009220-A1 | CELL CULTURE MEDIUM | CORREA PAULO N (CA) | 1993-05-13 | — | — | WO | claimed |
| CN-116286972-A | EIF2B5 gene knockout cell line and construction method and application thereof | 浙江大学医学院附属妇产科医院 | 2023-06-23 | — | — | CN | disclosed |
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |
| CN-1314964-C | Finger print allas used for controlling isatidis root, its preparation quality and medicine effect and its making method | GUANGZHOU BAIYUNSHAN CHINESE M (CN) | 2007-05-09 | — | — | CN | disclosed |
| CN-1282874-C | Quality controlling method for dangshen and preparation containing it | YUDAO SCIENCE & TECHNOLOGY DEV (CN) | 2006-11-01 | — | — | CN | disclosed |
| US-5397706-A | Serum-free basal and culture medium for hematopoietic and leukemia cells | CORREA PAULO N (CA) | 1995-03-14 | — | — | US | disclosed |
| WO-1993009220-A1 | CELL CULTURE MEDIUM | CORREA PAULO N (CA) | 1993-05-13 | — | — | WO | disclosed |
| US-4404368-A | Lyophilized phosphorylated nucleosides | ENS BIOLOGICALS INC. (CA) | 1983-09-13 | — | — | US | disclosed |
| EP-0058563-A1 | Lyophilized phosphorylated nucleosides | ens BIO LOGICALS INC. (CA) | 1982-08-25 | — | — | EP | disclosed |