Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30975396 | 0.82 | NOS1 (0.36) | METAP2EPAS1CYP1A2 | |
| SCHEMBL30536671 | 0.82 | FGFR1 (0.36) | METAP2CYP1A2 | |
| SCHEMBL22964672 | 0.82 | NOS1 (0.36) | METAP2EPAS1CYP1A2 | |
| SCHEMBL25369149 | 0.82 | FGFR1 (0.36) | METAP2CYP1A2 | |
| SCHEMBL31358029 | 0.79 | METAP2 (0.36) | METAP2CYP1A2 | |
| SCHEMBL24841969 | 0.77 | METAP2 (0.36) | METAP2 | |
| SCHEMBL31179208 | 0.76 | KDM4E (0.39) | METAP2EPAS1 | |
| SCHEMBL31248181 | 0.75 | METAP2 (0.37) | METAP2 | |
| SCHEMBL4731645 | 0.73 | METAP2 (0.40) | METAP2EPAS1CYP1A2 | |
| SCHEMBL31358108 | 0.73 | METAP2 (0.40) | METAP2EPAS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |