Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564464 | 1.00 | CD274 (0.39) | CD274PDCD1LG2CYP1A2CYP2D6UPP1 | |
| SCHEMBL846332 | 0.80 | PDXK (0.36) | ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL845675 | 0.72 | — | — | |
| SCHEMBL22743865 | 0.68 | CD274 (0.47) | CD274PDCD1LG2PDCD1ALDH1A1KMT2A | |
| SCHEMBL31111404 | 0.66 | KMT2A (0.34) | ALDH1A1KMT2ANPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL8544979 | 0.66 | KMT2A (0.34) | ALDH1A1KMT2ANPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL17748267 | 0.66 | CD274 (0.38) | CD274PDCD1LG2CYP1A2CYP2D6PDCD1 | |
| SCHEMBL20565231 | 0.66 | CD274 (0.42) | CD274PDCD1LG2CYP1A2CYP2D6PDCD1 | |
| SCHEMBL16176829 | 0.65 | PDE5A (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6101102 | 0.65 | KMT2A (0.42) | CD274PDCD1LG2CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285572-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119264073-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-110913858-B | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2024-09-24 | — | — | CN | disclosed |