Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544979 | 1.00 | KMT2A (0.34) | KMT2AMEN1HPGDPOLBALOX12 | |
| SCHEMBL8548916 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19971159 | 0.76 | ERN1 (0.33) | KMT2AMEN1MAPTALDH1A1CYP3A4 | |
| SCHEMBL845675 | 0.74 | — | — | |
| SCHEMBL846768 | 0.73 | KDM4E (0.30) | HPGDALDH1A1KDM4E | |
| SCHEMBL846767 | 0.73 | KDM4E (0.30) | HPGDALDH1A1KDM4E | |
| SCHEMBL8548155 | 0.72 | ALDH1A1 (0.33) | KMT2AMEN1MAPTALDH1A1CYP3A4 | |
| SCHEMBL8545018 | 0.72 | ADORA1 (0.41) | KMT2AMEN1HPGDPOLBMAPT | |
| SCHEMBL15434050 | 0.71 | CYP1A2 (0.38) | KMT2AMEN1MAPTALDH1A1CYP3A4 | |
| SCHEMBL1413327 | 0.71 | KMT2A (0.36) | KMT2AMEN1HPGDPOLBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285572-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119264073-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-110913858-B | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2024-09-24 | — | — | CN | disclosed |