SCHEMBL31111403

SCHEMBL31111403

COC(=O)[C@H](CC(=O)NCc1ccc(OC)cc1OC)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TAS1R3 Q7RTX0 2/20 0.48
▸ TAS1R1 Q7RTX1 2/20 0.48
▸ MDM2 Q00987 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ TP53 P04637 1/20 0.42
▸ POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30431821 0.84 MDM2 (0.49) TAS1R3TAS1R1MDM2MEN1KMT2A
SCHEMBL30863677 0.83 MDM2 (0.49) MDM2TP53
SCHEMBL10418082 0.83 MDM2 (0.49) MDM2TP53
SCHEMBL38666359 0.82 MDM2 (0.53) TAS1R3TAS1R1MDM2MEN1KMT2A
SCHEMBL25356267 0.80 MDM2 (0.48) TAS1R3TAS1R1MDM2MEN1KMT2A
SCHEMBL25356051 0.80 MDM2 (0.48) TAS1R3TAS1R1MDM2MEN1KMT2A
SCHEMBL25356048 0.80 MDM2 (0.48) TAS1R3TAS1R1MDM2MEN1KMT2A
SCHEMBL233300 0.79 MDM2 (0.47) MDM2MEN1KMT2AALDH1A1TP53
SCHEMBL13928511 0.79 MDM2 (0.47) MDM2MEN1KMT2AALDH1A1TP53
SCHEMBL31111371 0.79 MDM2 (0.48) MDM2MEN1KMT2AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673424-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS Regeneron Pharmaceuticals, Inc. (US) 2026-01-07 — — EP disclosed
WO-2024182268-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS REGENERON PHARMACEUTICALS, INC. (US) 2024-09-06 — — WO disclosed
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