Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115582 | 0.88 | GRIN1 (0.42) | OPRM1DRD2DRD3 | |
| SCHEMBL24608764 | 0.84 | GRIN1 (0.44) | OPRM1DRD2DRD3 | |
| SCHEMBL15863115 | 0.84 | GRIN1 (0.47) | OPRM1 | |
| SCHEMBL11920692 | 0.83 | OPRM1 (0.40) | OPRM1DRD2DRD3 | |
| SCHEMBL31114112 | 0.80 | OPRM1 (0.46) | OPRM1DRD2DRD3CYP2D6 | |
| SCHEMBL29967521 | 0.79 | OPRM1 (0.65) | OPRM1DRD2DRD3 | |
| SCHEMBL26638893 | 0.79 | OPRM1 (0.65) | OPRM1DRD2DRD3 | |
| SCHEMBL3973883 | 0.79 | HSD11B1 (0.37) | OPRM1 | |
| SCHEMBL28869098 | 0.78 | OPRM1 (0.52) | OPRM1DRD2DRD3 | |
| SCHEMBL536557 | 0.77 | OPRM1 (0.53) | OPRM1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024186915-A1 | DUAL-TARGET MU OPIOID AND DOPAMINE D3 RECEPTORS LIGANDS PREPARATION AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-09-12 | — | — | WO | disclosed |