Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25130121 | 0.98 | KDM4E (0.34) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL868382 | 0.83 | — | — | |
| SCHEMBL26349405 | 0.80 | CA1 (0.34) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL17550590 | 0.79 | — | — | |
| SCHEMBL22883324 | 0.77 | HDAC3 (0.38) | — | |
| SCHEMBL19658266 | 0.77 | MAPT (0.46) | KDM4EPAOXTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL18519881 | 0.76 | TSHR (0.33) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL22430280 | 0.76 | TERT (0.37) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL21664183 | 0.76 | TERT (0.37) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL17760929 | 0.74 | LMNA (0.43) | TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401517-A | PLpro inhibitors | 上海华汇拓医药科技有限公司 | 2024-07-26 | — | — | CN | disclosed |