Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682238 | 1.00 | ESR2 (0.39) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL21682209 | 0.79 | BACE1 (0.50) | MEN1KMT2AALDH1A1CYP1A2HTT | |
| SCHEMBL30002881 | 0.79 | BACE1 (0.50) | MEN1KMT2AALDH1A1CYP1A2HTT | |
| SCHEMBL31123709 | 0.77 | TLR8 (0.49) | MEN1KMT2AALDH1A1GAAACHE | |
| SCHEMBL21683406 | 0.73 | CA12 (0.45) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL18572912 | 0.73 | ESR2 (0.42) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL31296110 | 0.70 | MEN1 (0.52) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6240232 | 0.70 | MEN1 (0.52) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10733095 | 0.68 | ESR2 (0.50) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10733080 | 0.68 | ESR2 (0.50) | ESR2ESR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |