SCHEMBL6240232

SCHEMBL6240232

Oc1ccc2cc3ccc(O)cc3nc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ALDH1A1 P00352 3/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
ESR2 Q92731 4/20 0.52
ACHE P22303 2/20 0.50
F2 P00734 1/20 0.50
LMNA P02545 1/20 0.50
CHRM2 P08172 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
MAOA P21397 1/20 0.50
DRD1 P21728 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
OPRM1 P35372 1/20 0.50
DRD3 P35462 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296110 1.00 MEN1 (0.52) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL10733095 0.97 ESR2 (0.50) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL10733080 0.97 ESR2 (0.50) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL11067469 0.89 ALDH1A1 (0.65) MEN1KMT2AALDH1A1CASP1CASP7
Sulfuric Acid SCHEMBL10726991 0.89 ESR2 (0.44) MEN1KMT2AALDH1A1CASP1CASP7
Hydrochloric Acid SCHEMBL28313625 0.87 ALDH1A1 (0.62) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL11058889 0.82 BACE1 (0.52) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL11058519 0.82 KDM4E (0.51) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL14077239 0.80 ALDH1A1 (0.54) MEN1KMT2AALDH1A1CASP1CASP7
SCHEMBL2368334 0.80 ALDH1A1 (0.54) MEN1KMT2AALDH1A1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3759171-B9 AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2023-05-24 EP claimed
EP-3759171-B1 AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2023-02-22 EP claimed
EP-0031407-B1 SUBSTITUTED 3,6 BIS-(AMINOALKOXY)ACRIDINES, AND A PROCESS FOR THEIR PREPARATION AMERICAN CYANAMID COMPANY (US) 1987-04-22 EP claimed
CN-106471067-B Azetidine substituted fluorescent compounds 霍华德休斯医学研究所 2020-12-08 CN disclosed
EP-3126451-B1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS HUGHES HOWARD MED INST (US) 2020-09-09 EP disclosed
US-20190107534-A1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS HOWARD HUGHES MEDICAL INSTITUTE 2019-04-11 US disclosed
US-10161932-B2 Azetidine-substituted fluorescent compounds HOWARD HUGHES MEDICAL INSTITUTE (US) 2018-12-25 US disclosed
US-20180284105-A1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS HOWARD HUGHES MEDICAL INSTITUTE 2018-10-04 US disclosed
US-10018624-B1 Azetidine-substituted fluorescent compounds HOWARD HUGHES MEDICAL INSTITUTE (US) 2018-07-10 US disclosed
US-20180172677-A1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS HOWARD HUGHES MEDICAL INSTITUTE 2018-06-21 US disclosed
US-9933417-B2 Azetidine-substituted fluorescent compounds HOWARD HUGHES MEDICAL INSTITUTE (US) 2018-04-03 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4696936-A 3,6-bis (substituted) acridine N-oxides and N,N-dioxides and methods of restoring, stimulating or enhancing the immune system with them AMERICAN CYANAMID COMPANY (US) 1987-09-29 US disclosed
US-4696935-A 3,6-BIS(2-(PIPERIDINO)ETHOXY)ACRIDINE AMERICAN CYANAMID COMPANY (US) 1987-09-29 US disclosed
EP-0031407-B1 SUBSTITUTED 3,6 BIS-(AMINOALKOXY)ACRIDINES, AND A PROCESS FOR THEIR PREPARATION AMERICAN CYANAMID COMPANY (US) 1987-04-22 EP disclosed
EP-0180812-A2 3,6 Bis(substituted) acridine derivatives AMERICAN CYANAMID COMPANY (US) 1986-05-14 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4314061-A Certain 3,6-bis-(heteroaminoalkoxy) acridines AMERICAN CYANAMID COMPANY 1982-02-02 US disclosed
EP-0031407-A1 Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation AMERICAN CYANAMID COMPANY (US) 1981-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180284105-A1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS AANAT, HNMT, CHAT MEN1 2400/4885KMT2A 3092/4885ALDH1A1 298/4885
US-10018624-B1 Azetidine-substituted fluorescent compounds AANAT, HNMT, CHAT MEN1 2400/4885KMT2A 3092/4885ALDH1A1 298/4885
US-20180172677-A1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS AANAT, HNMT, CHAT MEN1 2400/4885KMT2A 3092/4885ALDH1A1 298/4885
US-20190107534-A1 AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS AANAT, HNMT, CHAT MEN1 2400/4885KMT2A 3092/4885ALDH1A1 298/4885
US-10161932-B2 Azetidine-substituted fluorescent compounds AANAT, HNMT, CHAT MEN1 2400/4885KMT2A 3092/4885ALDH1A1 298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.