Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31296110 | 0.97 | MEN1 (0.52) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL6240232 | 0.97 | MEN1 (0.52) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL10733080 | 0.95 | ESR2 (0.50) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| Sulfuric Acid SCHEMBL10726991 | 0.86 | ESR2 (0.44) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL11067469 | 0.86 | ALDH1A1 (0.65) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| Hydrochloric Acid SCHEMBL28313625 | 0.84 | ALDH1A1 (0.62) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL11058889 | 0.80 | BACE1 (0.52) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL11058519 | 0.80 | KDM4E (0.51) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL2368334 | 0.78 | ALDH1A1 (0.54) | ESR2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL14077239 | 0.78 | ALDH1A1 (0.54) | ESR2MEN1KMT2AALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031407-B1 | SUBSTITUTED 3,6 BIS-(AMINOALKOXY)ACRIDINES, AND A PROCESS FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1987-04-22 | — | — | EP | claimed |
| EP-0031407-A1 | Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-07-08 | — | — | EP | claimed |
| US-4696935-A | 3,6-BIS(2-(PIPERIDINO)ETHOXY)ACRIDINE | AMERICAN CYANAMID COMPANY (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0031407-B1 | SUBSTITUTED 3,6 BIS-(AMINOALKOXY)ACRIDINES, AND A PROCESS FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1987-04-22 | — | — | EP | disclosed |
| US-4314061-A | Certain 3,6-bis-(heteroaminoalkoxy) acridines | AMERICAN CYANAMID COMPANY | 1982-02-02 | — | — | US | disclosed |
| EP-0031407-A1 | Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-07-08 | — | — | EP | disclosed |