Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 14/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123788 | 0.86 | PRMT5 (0.42) | LMNAALDH1A1PRMT5WDR77 | |
| SCHEMBL31123742 | 0.86 | ADK (0.42) | ADKSLC29A1HASPIN | |
| SCHEMBL31123702 | 0.83 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL25109983 | 0.80 | ADK (0.44) | ADKSLC29A1LMNAHASPINALDH1A1 | |
| SCHEMBL30003568 | 0.80 | ADK (0.44) | ADKSLC29A1LMNAHASPINALDH1A1 | |
| SCHEMBL2787845 | 0.76 | ADK (0.52) | ADKSLC29A1LMNAALDH1A1 | |
| SCHEMBL18595659 | 0.76 | ADK (0.52) | ADKSLC29A1LMNAALDH1A1 | |
| SCHEMBL13021362 | 0.76 | ADK (0.52) | ADKSLC29A1LMNAALDH1A1 | |
| SCHEMBL12374608 | 0.76 | ADK (0.52) | ADKSLC29A1LMNAALDH1A1 | |
| SCHEMBL30050679 | 0.76 | ADK (0.52) | ADKSLC29A1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |