SCHEMBL31123786

SCHEMBL31123786

Fc1cnc2[nH]c(Cl)ncc1-2

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.33
DDO Q99489 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3389797 0.74
SCHEMBL2206478 0.68 PTGES (0.31)
SCHEMBL25212875 0.67
SCHEMBL13649272 0.60 JAK2 (0.42) DAO
SCHEMBL3392370 0.59
SCHEMBL3394187 0.54 GRIN2D (0.41) DAO
SCHEMBL2763121 0.54
SCHEMBL24741850 0.53 SMN1; SMN2 (0.38) DAODDO
SCHEMBL1016281 0.53
SCHEMBL11542411 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112805006-B PRMT5 inhibitors 默沙东有限责任公司 2024-09-24 CN disclosed