Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25332972 | 0.82 | SIRT5 (0.40) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL16847608 | 0.80 | MAPT (0.49) | SIRT5SIRT2SIRT1SIRT3TGM2 | |
| SCHEMBL19017845 | 0.80 | MAPT (0.49) | SIRT5SIRT2SIRT1SIRT3TGM2 | |
| SCHEMBL31123853 | 0.80 | KLKB1 (0.42) | SIRT2SIRT1KLKB1PLG | |
| SCHEMBL30468998 | 0.80 | SIRT2 (0.42) | SIRT5SIRT2SIRT1SIRT3TGM2 | |
| SCHEMBL18100002 | 0.79 | SIRT2 (0.44) | SIRT5SIRT2SIRT1SIRT3TGM2 | |
| SCHEMBL5550454 | 0.79 | KMT2A (0.46) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL5550449 | 0.79 | KMT2A (0.46) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL17661281 | 0.77 | SIRT2 (0.50) | SIRT2SIRT1SIRT3TGM2 | |
| SCHEMBL5545902 | 0.77 | ANPEP (0.46) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647407-A | Antibody conjugated chemical degradation inducers and methods thereof | 基因泰克公司 | 2024-09-13 | — | — | CN | disclosed |