SCHEMBL31124405

SCHEMBL31124405

C[Si](C)(C)CCOCn1ccc2c(OC3CCNC3)ncnc21

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 18/20 0.42
SCN5A Q14524 11/20 0.42
KCNH2 Q12809 6/20 0.42
PIK3CD O00329 1/20 0.39
CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17545930 0.94 SCN9A (0.41) SCN9ASCN5AKCNH2
SCHEMBL27028314 0.78 CHEK2 (0.33)
SCHEMBL20893945 0.78 ALDH1A1 (0.36) SCN9ASCN5AKCNH2
SCHEMBL17545937 0.77 PIK3CD (0.42) SCN9ASCN5AKCNH2PIK3CDCHRM1
SCHEMBL17467044 0.76 SCN5A (0.33) SCN9ASCN5AKCNH2CHRM1
SCHEMBL31124315 0.76 JAK3 (0.35)
SCHEMBL20183873 0.76 GPR119 (0.51) SCN9ASCN5AKCNH2PIK3CD
SCHEMBL31124313 0.75 PIK3CD (0.54) PIK3CD
SCHEMBL17527387 0.74 PIK3CD (0.49) PIK3CD
SCHEMBL18419032 0.74 PIK3CD (0.49) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175998-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF DUNAD THERAPEUTICS, LTD. (GB) 2024-08-29 WO disclosed