Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9871919 | 0.98 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL9871924 | 0.98 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL6140060 | 0.78 | RAB9A (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL6160201 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL6556168 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL10801184 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL256048 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL11105985 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2989454 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL3260153 | 0.78 | RAB9A (0.62) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | disclosed |