Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556168 | 1.00 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL1165357 | 0.81 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL29141002 | 0.79 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL6140060 | 0.78 | RAB9A (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2989454 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL31124655 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL10801184 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL11105985 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL256048 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL11105983 | 0.78 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505156-B1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | CONSORTIUM ELEKTROCHEM IND (DE) | 2005-12-07 | — | — | EP | disclosed |
| EP-1505156-A1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | Consortium für elektrochemische Industrie GmbH (DE) | 2005-02-09 | — | — | EP | disclosed |
| CN-1188401-C | Heterocyclic amide compound and its pharmaceutical use | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2005-02-09 | — | — | CN | disclosed |
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| CN-1131210-C | Heterocyclic amide compound and medical use thereof | MITSUBISHI SEIYAKU CO LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| US-6528514-B1 | Pyrimidin-4-one-5-amino-3-alkylcarboxamidomethyl compounds | WELFIDE CORPORATION (JP) | 2003-03-04 | — | — | US | disclosed |
| CN-1304931-A | Heterocyclic amide compound and medical use thereof | EFUKU CO LTD (JP) | 2001-07-25 | — | — | CN | disclosed |
| EP-1062949-A1 | IgE ANTIBODY PRODUCTION INHIBITORS AND AUTOIMMUNE DISEASES INHIBITORS | Welfide Corporation (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| CN-1188472-A | Heterocyclic amide compound and medical use thereof | GREEN CROSS CORP (JP) | 1998-07-22 | — | — | CN | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |