SCHEMBL31124658

SCHEMBL31124658

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)CC

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 5/20 0.67
OPRM1 P35372 1/20 0.67
OPRK1 P41145 1/20 0.67
NTSR1 P30989 7/20 0.67
NTSR2 O95665 5/20 0.67
SORT1 Q99523 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421754 0.93 NTSR1 (0.74) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL1421733 0.93 NTSR1 (0.74) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL18911388 0.90 OPRD1 (0.60) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL18911387 0.90 OPRD1 (0.60) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL30921554 0.90 SLC6A2 (0.67) NTSR1NTSR2SORT1
SCHEMBL31457347 0.89 NTSR1 (0.64) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL30880437 0.88 NTSR1 (0.82) NTSR1NTSR2SORT1
SCHEMBL1421931 0.88 OPRD1 (0.69) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL1421888 0.88 OPRD1 (0.69) OPRD1OPRM1OPRK1NTSR1NTSR2
SCHEMBL1421906 0.88 OPRD1 (0.69) OPRD1OPRM1OPRK1NTSR1NTSR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119139448-B Lumbricus peptide and medical application thereof 山东中医药大学 2025-05-16 CN disclosed
CN-119139448-A Lumbricus peptide and medical application thereof 山东中医药大学 2024-12-17 CN disclosed
CN-118684736-B Lumbricus peptide and its preparation method and use for relieving cough and asthma 山东中医药大学 2024-10-29 CN disclosed
CN-118684736-A Lumbricus peptide and its preparation method and use for relieving cough and asthma 山东中医药大学 2024-09-24 CN disclosed