Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 4/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.34 |
| ▸ | MGMT | P16455 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158500 | 0.87 | CDK2 (0.53) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL28204452 | 0.81 | CDK2 (0.35) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL12069183 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL12602353 | 0.76 | PDK2 (0.31) | TDP1 | |
| SCHEMBL28204453 | 0.75 | TDP1 (0.45) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL22632213 | 0.75 | CDK2 (0.41) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL28277511 | 0.74 | CDK2 (0.39) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL439475 | 0.74 | CDK2 (0.61) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL4572376 | 0.71 | CDK1 (0.66) | CDK2CDK1CDK4MEN1KMT2A | |
| SCHEMBL14361098 | 0.70 | ADORA2A (0.33) | CDK2CCNA2CCNA1DPP4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852029-B | Method for preparing 2-amino-4, 6-dichloro-5-carboxamido pyrimidine | 苏州开元民生科技股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118852029-A | Method for preparing 2-amino-4, 6-dichloro-5-carboxamido pyrimidine | 苏州开元民生科技股份有限公司 | 2024-10-29 | — | — | CN | disclosed |