Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.61 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.61 |
| ▸ | CDK1 | P06493 | 6/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.47 |
| ▸ | MGMT | P16455 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121357 | 0.92 | CDK2 (0.55) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL29473573 | 0.83 | CDK2 (0.52) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL4160357 | 0.83 | CDK2 (0.52) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL9443788 | 0.82 | CDK2 (0.47) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL6206701 | 0.79 | CDK2 (0.48) | CDK2CCNA2CCNA1CDK1CDK4 | |
| Nitrous Acid SCHEMBL29168822 | 0.79 | CDK2 (0.48) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL656566 | 0.79 | CDK2 (0.48) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL7767432 | 0.78 | CDK2 (0.45) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL7766477 | 0.78 | CDK2 (0.45) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL14490772 | 0.78 | CDK2 (0.47) | CDK2CCNA2CCNA1CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239790-A | Carboxyl end-capped hyperbranched polyamide based on furandicarboxylic acid, preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-09 | — | — | CN | claimed |
| CN-113173887-A | Synthetic method of triamterene intermediate | 河北利德检测技术有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-107629055-A | A kind of triamterene compound and preparation method thereof | 湖北美林药业有限公司 | 2018-01-26 | — | — | CN | claimed |
| CN-106967069-A | A kind of preparation method of triamterene | 盐城市麦迪科化学品制造有限公司 | 2017-07-21 | — | — | CN | claimed |
| CN-105219008-B | The composition of a kind of SEBS reclaimed materials and by its prepared automobile SEBS ground cushion | 嘉兴市博尔塑胶有限公司 | 2017-07-07 | — | — | CN | claimed |
| US-6846525-B2 | Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds | XEROX CORPORATION (US) | 2005-01-25 | — | — | US | claimed |
| US-20040202825-A1 | RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS | XEROX CORPORATION | 2004-10-14 | — | — | US | claimed |
| EP-1073660-B1 | YELLOW PTERIDINE HAVING A HUE-ANGLE OF AT LEAST 98 | CIBA SC HOLDING AG (CH) | 2004-06-09 | — | — | EP | claimed |
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | claimed |
| EP-0574906-B1 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO (JP) | 2001-08-22 | — | — | EP | claimed |
| EP-0673783-A2 | Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| EP-0574906-A2 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-12-22 | — | — | EP | claimed |
| US-4831139-A | REACTING MALONODINITRILE WITH SUBSTITUTED AMIDINE SALTS IN AQUEOUS ACID MEDIUM IN PRESENCE OF NITRITE SALTS | LONZA LTD. (CH) | 1989-05-16 | — | — | US | claimed |
| US-4731436-A | Thermosetting crosslinked imide resin from bis-imide and polyamine | BTL SPECIALTY RESINS CORPORATION (US) | 1988-03-15 | — | — | US | claimed |
| EP-0115325-B1 | PROCESS OF PREPARATION OF 2-SUBSTITUTED-5-NITROSO-4,6-DIAMINO-PYRIMIDINES | LONZA AG (CH) | 1987-07-29 | — | — | EP | claimed |
| EP-0225614-A2 | Process for the preparation of 4-substituted 5-nitroso-4,6-diamino-pyrimidines | LONZA AG (CH) | 1987-06-16 | — | — | EP | claimed |
| EP-0115325-A2 | Process of preparation of 2-substituted-5-nitroso-4,6-diamino-pyrimidines | LONZA AG (CH) | 1984-08-08 | — | — | EP | claimed |
| US-4247693-A | Process for preparing 2,4,5,6-tetraaminopyrimidine sulfate | AMERICAN CYANAMID COMPANY (US) | 1981-01-27 | — | — | US | claimed |
| US-4167633-A | Preparation of 2,4,5,6-tetraaminopyrimidine from 2,4,6-triaminopyrimidine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1979-09-11 | — | — | US | claimed |
| US-4145548-A | Method for the production of 5-nitroso-2,4,6-triaminopyrimidine | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-03-20 | — | — | US | claimed |