Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 9/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492681 | 0.87 | GLA (0.46) | GAATSHRGLAPOLBPTPN11 | |
| SCHEMBL31125280 | 0.81 | KDM1A (0.40) | PTPN11HTR2CARKDM1A | |
| SCHEMBL31357853 | 0.78 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL287497 | 0.75 | PTPN11 (0.41) | PTPN11ALDH1A1CRBNMAPK1 | |
| SCHEMBL30966827 | 0.75 | CYP3A4 (0.42) | GAATSHRPOLBPTPN11KDM4E | |
| SCHEMBL31125223 | 0.73 | KDM4E (0.46) | GAAPTPN11ARKDM4EMEN1 | |
| SCHEMBL324114 | 0.72 | GLA (0.55) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL30084901 | 0.72 | GLA (0.55) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL16761967 | 0.71 | TSHR (0.50) | GAATSHRGLAPOLBHTR2C | |
| SCHEMBL31125221 | 0.71 | CYP3A4 (0.42) | GAATSHRPOLBPTPN11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852145-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |