Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | CTSD | P07339 | 3/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287497 | 0.86 | PTPN11 (0.41) | PTPN11BACE1CTSDBACE2REN | |
| SCHEMBL30966827 | 0.79 | CYP3A4 (0.42) | PTPN11CYP3A4IKBKBPGK1 | |
| SCHEMBL20079214 | 0.79 | BACE1 (0.38) | PTPN11BACE1CTSDBACE2REN | |
| SCHEMBL31125232 | 0.78 | GAA (0.42) | PTPN11 | |
| SCHEMBL31125223 | 0.77 | KDM4E (0.46) | PTPN11CYP3A4IKBKBPGK1 | |
| SCHEMBL31125221 | 0.75 | CYP3A4 (0.42) | PTPN11CYP3A4IKBKBPGK1 | |
| SCHEMBL13646423 | 0.75 | KDM4E (0.37) | BACE1CYP3A4 | |
| SCHEMBL5492681 | 0.75 | GLA (0.46) | PTPN11 | |
| SCHEMBL18233545 | 0.75 | REN (0.38) | PTPN11BACE1CTSDBACE2REN | |
| SCHEMBL31125215 | 0.74 | BACE1 (0.43) | PTPN11BACE1CTSDBACE2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431327-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |